AVM® – Aseptic Validation Medium – is the registered brand name of the Linden Grain medium in the Döhler Microsafety Design® portfolio.
This medium allows standardised detection of beverage-spoiling bacteria, yeast and mould for validating aseptic filling lines for beverages with a pH value of between 4.0 and 6.5, such as soft drinks, juices and even dairy products.
In the production of beverages with a low acid content, the filling process and the filling line itself may be a source of contamination with beverage-spoiling microorganisms.
To allow possible weak points to be recognised, the filling process on aseptic lines needs to be examined and validated during commissioning or if major changes are made, such as in maintenance or service. In addition, annual revalidation is recommended even for unchanged filling processes in order to discover any contamination sources early on.
Validation should be conducted with standardised products of standardised quality to guarantee that the results are comparable and reproducible. The use of AVM® is not merely based on microbiological investigation of random samples of finished products and statistical extrapolation of the results – furthermore, it assesses the entire filling process. This allows trace and scattered infections to be detected, too.
AVM® has an ideal nutrient composition and allows the pH value to be set flexibly for certain product variations.
AVM® is available in four product varieties:
AVM® Liquid is a ready-to-use, purely vegetable-based, liquid Linden Grain medium for immediate use, and is provided in a tank train.
AVM® Concentrated Broth is a liquid, five-fold concentrated Linden Grain medium delivered in a container. The pH value of the concentrate needs to be set through dilution with water once the ready-to-use medium has been produced.
AVM® veg Powder is a Linden Grain medium in powder form for the production of a liquid medium. Using purely vegetable-based raw materials prevents animal-based ingredients from being introduced into the beverage production process. The pH value adjustment makes it possible to detect beverage-spoiling microorganisms in slightly sour beverages. It is available in 20 kg units in sealed plastic buckets.
AVM® Powder is a Linden Grain medium in powder form for the production of a liquid medium. It is available in 20 kg units in sealed plastic buckets. The pH value is also set individually by the customer.
AVM® offers you the following user benefits:
Flexible formats for immediate use – ready-to-use or five-fold concentrated liquid medium for immediate use, or standard or vegetable-based powder with excellent solubility and simple handling for storage and use as needed.
|Product name||Order number||Description||Content|
|AVM® Broth||2.04705.050||Liquid, purely vegetable-based Linden Grain medium|
Application: Qualitative detection as part of
validation of aseptic filling facilities
|Min. 3 tonnes (tank train)|
|AVM® Concentrated Broth||2.04755.521|| Concentrated liquid, purely vegetable-based Linden Grain medium |
for production of AVM® broth
|Min. 3 tonnes (container)|
|AVM® veg Powder||8.50872.872||Easily soluble, purely vegetable-based powder for production of|
AVM® veg Broth – liquid Linden Grain medium
20 kg (bucket)
|AVM® Powder||2.04704.872||Easily soluble powder for production of|
AVM® Broth – liquid Linden Grain medium
20 kg (bucket)
Please contact the following distributors or Döhler directly.
|China||Shanghai Sunny Biological Science |
and Technology Co.Ltd
|Room 1706, No.1619 Dalian road, |
|firstname.lastname@example.org||+86 021 021 65190298 8016|
|Singapore||Avantor SEA|| |
18 Gul Drive
|email@example.com||+66 95 5626963|
|Mongolia||Monbiopharm Co. Ltd.||Sukhbaatar District - 4 khoroo 1-69 |
|firstname.lastname@example.org||+976 11 330234|
|Brazil||Prozyn Indústria e Comércio Ltda||Rua Dr. Paulo Leite de Oliveira, 199 |
|email@example.com||+55 11 3732 0000|
|Brazil||Merse||R. Domingos Cazotti, 284 |
Jd. Santa Genebra - Campinas/SP
|firstname.lastname@example.org||+55 193733 3800|
|USA||Weber Scientific||2732 Kuser Road |
Hamilton, NJ, 08691
|email@example.com||+1 609 249 1408|
|USA||White Labs||9495 Candida St |
San Diego, CA 92126
+1 858 527 7358
|USA||BSG||9650 East 40th Ave |
Denver, CO 80238
|firstname.lastname@example.org||+1 303 574 8955|
|Canada||ProSource Scientific||5370 Canotek Road Unit 11 |
Ontario K1J 9E7
|email@example.com||+1 866 939 9959|
|France||Laboratories Humeau||ZA Gesvrine - 4 rue Kepler BP 4125 |
44241 La Chapelle-sur-Erdre Cedex
|firstname.lastname@example.org||+33 2 40 93 53 53|
|France||Brewpark sas||Rue des Colinettes |
ZI Mardeuil, 51530 Mardeuil
|email@example.com||+33 3 26 55 82 89|
|Italy||Sacco S.r.l.||Via A. Manzoni 29/A |
|firstname.lastname@example.org||+39 031 8866 607|
|Latvia||SnapTest.LV SIA||Valmieras iela 31B |
|email@example.com||+371 26 53 47 45|
|United Kingdom||Trafalgar Scientific Ltd||190 Waterside Rd, Leicester LE5 1QZfirstname.lastname@example.org||+44 116 287 9460|
|Netherlands||SBI Europe||Kraaiondonk 44 |
5428 NZ Venhorst
|email@example.com||+31 413 783 880|
|all European countries||VWR International||Hilpertstraße 20a |
|firstname.lastname@example.org||+49 800 702 0007|
|all other countries||Döhler GmbH||Riedstraße 7-9 |
|email@example.com||+49 (0)6151 3060|